Experimental models for hepatic encephalopathy
نویسندگان
چکیده
منابع مشابه
Experimental models for hepatic encephalopathy.
Although there are many models for animal testing, the ideal model for chronic liver disease involving hepatic encephalopathy has not been described yet. Different problems associated with the models have led researchers to develop their own, sometimes unique experimental models, which makes difficult the comparison between the results of the conducted studies (1). Hepatic encephalopathy (HE) d...
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The serious neuropsychological repercussions of hepatic encephalopathy have led to the creation of several experimental models in order to better understand the pathogenesis of the disease. In the present investigation, two possible causes of hepatic encephalopathy, cholestasis and portal hypertension, were chosen to study the behavioral impairments caused by the disease using an object recogni...
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Hepatic encephalopathy (HE) is a complex neuropsychiatric syndrome that appears as a consequence of acute or chronic liver dysfunction. Ammonia is considered central to its pathogenesis, but the factors contributing to the neurological dysfunction the disorder entails remain unclear (Butterworth et al., 2002). In humans with HE, it has been suggested that the basal ganglia may be selectively af...
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The liver is the most important organ for the well-functioning of other organs because of its vital role in nutrition, metabolism and secretion. Any disturbance in normal homeostasis of liver as it happens in acute liver failure (ALF) and chronic liver disease (cirrhosis) will lead to extra hepatic manifestations of liver disease, among them one is encephalopathy. And this encephalopathy caused...
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ژورنال
عنوان ژورنال: Revista Española de Enfermedades Digestivas
سال: 2011
ISSN: 1130-0108
DOI: 10.4321/s1130-01082011001000006